Dihydroergotamine stability

Cases asserting a duty to assist rivals, "conduct is not `exclusionary' or `predatory' would make no economic sense for the defendant but for its tendency to eliminate or lessen competition." 44 Alternatively, the court might have explicitly attempted to balance the anticompetitive aspects of 3M's price structure i.e., the exclusionary effects exceeding those of an above-cost single-product discount ; against the procompetitive benefits of that pricing structure. Such an inquiry would have been similar to the usual weighing of procompetitive benefits against anticompetitive harms that occurs in applying Section 1's rule of reason, and may have been close to the Section 2 balancing process suggested by the D.C. Circuit in Microsoft. 45 It would surely have included the beneficial aspects of the price reductions on the procompetitive side of the calculus. But the court did neither because it skipped the essential first step of sorting out whether 3M's pricing conduct had any effects beyond those of a per se lawful above-cost single-product price reduction. This placed 3M in an untenable position of having not only to justify its choice of pricing structure but to show that the structure achieved efficiencies equal to the millions in price reductions 3M offered its customers. And it also placed LePage's' claims before the jury in a context where the court's jury instructions offered precious little guidance for distinguishing lawful price competition by a monopolist form illegal monopolization. The jury was asked whether 3M's conduct tended to "impair the.
Dihydroergotamine cluster headache
4291 PATIENT SATISFACTION WITH CARE PROVIDED IN TWO RHEUMATOLOGY CLINICS Jackie Hochman, Dominique Ibanez, Simon Carrette University of Toronto Rheumatology Clinics, Toronto Western Hospital ; Objective The aim of this study was to measure patient satisfaction with care provided in two academic rheumatology out-patient clinics. Methods Patient satisfaction was measured using the Leeds Satisfaction Questionnaire LSQ ; that has been validated in rheumatology patients. The LSQ measures six dimensions of care: giving of information; empathy with the patient; attitude towards the patient; access to and continuity with the caregiver; technical quality and competence; and overall satisfaction. It was distributed to 75 consecutive patients of 18 participating physicians. Return envelopes identified physicians with randomly derived numbers to maintain confidentiality. Patients were assured of anonymity. Group and individual physician scores were computed for each dimension of care. Individual results were handed to each physician with comparisons to group scores and other physicians' global scores. Comparisons of each dimension between physicians were obtained through linear regression analysis, adjusting for first versus follow-up visit, and staff versus trainee care provider. Results Obtained and Conclusion 623 patients returned questionnaires 46.1% response rate ; . The majority of patients, 499 83.2% ; received follow-up care, while 101 patients 16.8% ; received "first-visit" care. Satisfaction scores for follow-up and first visit care were similar in all domains. Satisfaction scores were significantly higher in all domains when patients were seen first by a staff rheumatologist. There was no significant difference in patient satisfaction between the two sites. Overall satisfaction with the group of physicians was relatively high at 7.8 maximum 10 ; . Scores for individual physicians varied ie. overall satisfaction ranged from 7.8 to 8.7. Statistical differences were seen between physicians' scores in all domains aside from technical quality and competence. Brief Conclusion: Overall, patients were satisfied with care received at two out-patient rheumatology clinics. Satisfaction was higher with care received first from a staff rheumatologist rather than a trainee. There was a range in satisfaction with care provided by individual physicians in multiple domains. Knowledge of individual scores may lead to a change in physician behavior and subsequent improvement in patient satisfaction.

Dihydroergotamine for headache

The performance of an antibody test used in routine diagnostics, namely an indirect ELISA, was evaluated with respect to its ability to detect cattle pregnant with PI foetuses III ; . This was done by analysing a data set including records on 2, 162 cow-calf pairs where the cow had been tested antibody positive to BVDV during pregnancy while clearing the herd from the infection ; and where also her calf had been tested for antibodies and virus. The sensitivity and specificity of the test was modelled at 12 different decision thresholds corresponding to OD values from 0.5 to 1.6 with increments of 0.1 ; using a generalised linear mixed models approach binomial error, logit link ; . The dependent variable was the test result + - ; at each decision threshold and the gold standard the calf's BVDV status ; was included in the model as one of the covariates. Other covariates included in the models were month of gestation, specimen blood milk ; and lactation number. To account for dependence between observations within herds ; , a random effect of herd was included Middot; do not take vfend if you are taking any of the following drugs: · terfenadine seldane ; or astemizole hismanal · cisapride propulsid · pimozide orap · quinidine cardioquin, quinora, quinidex, quinaglute, quin-release, quin-g · sirolimus rapamune · efavirenz sustiva · ritonavir norvir · rifabutin mycobutin ; or rifampin rifadin, rimactane · carbamazepine tegretol, others · phenobarbital; or · an ergot medication such as ergotamine ergomar, cafergot, ercaf, wigraine, others ; or dihydroergotamine e.
Dihydroergotamine tartrate
The 24-hour urinary 5-HIAA level. biologic response is often correlated. Could account for the decrease in pulmonary pressure noted by these investigators. `"" et al's studied in patients catheterization. the pharmacologic valvular Their heart finding effects, disease that infuof with and dilaudid. Use of these two drugs together may stop the headaches. No clinical trials have been published, however, to prove the efficacy of this combination. d. Divalproex sodium Depakote ; can relieve migraine headaches in patients who do not respond to beta blockers or antidepressants. The starting dose is usually 250 mg a day with a gradual increase up to 2000 mg in a divided dose. Potential side effects include nausea, drowsiness and weight gain. Other anticonvulsants that can be useful in the prophylaxis of migraines are topiramate Topamax ; and gabapentin Neurontin ; . e. Calcium channel blockers are sometimes effective for migraines, but are more likely to benefit a patient with cluster headaches. NSAIDs can sometimes be effective for prevention of migraines. Botulinum toxin Botox ; injections into pericranial and cervical muscles can be effective in prevention of migraines with almost no side effects and the duration of the effect of 2-4 months. Magnesium was found to be effective in prevention of migraines in two placebo-controlled, double-blind studies. The dose is 400-600 mg a day of magnesium oxide or chelated magnesium magnesium glycinate ; taken every day with food. A single double-blind study suggests that a megadose 400 mg a day ; of riboflavin can prevent migraines after 2-3 months of daily intake. Pharmacological treatment for Cluster Headaches Abortive therapy Treatment of cluster headaches begins with measures designed to reduce pain of each attack while prophylactic drugs take effect. 1. The most benign and frequently effective treatment is inhalation of oxygen. It is done through a mask not nasal prongs ; using 100% oxygen at 8-10 liters per minute. It should be used for patients who get most of their attacks at home. If headaches occur during the day, patients can store another oxygen tank at work. 2. Sumatriptan Imitrex ; injection is very effective in most patients and has few side effects. It can also be self-administered by the patient using an autoinjector. 3. Ergotamine Cafergot, Wigraine, Ergostat ; can abort a cluster headache in up to 75% of patients. It is best given by a suppository or sublingually to provide rapid onset of action. Dihydroergotamine DHE-45 ; is given only by injection and can be self-administered by the patient. Prophylactic therapy 1. A short course of prednisone will frequently stop the cluster. Dosage is.

Dihydroergotamine mesylate iv

We have established a reproducible in vivo system for studying the transport of substances across the common carotid artery of rabbits. The arterial endothelium has been preserved in an intact state, and no morphological evidence of vascular injury has been apparent. Important ingredients for the preservation of the endothelium have included minimal manipulation or dissection of the adventitia other than for ligation of the arterial branches ; , perfusion of the artery under pressure, and use of enriched tissue culture medium. Molecular transport across the endothelium and total arterial wall is a complex process and can involve several different pathways, including passage via intercellular junctions, pinocytotic vesicles, transendothelial channels, or diffusion through cell membranes. Under normal circumstances, macromolecules such as albumin are thought to be transported primarily in vesicles Chien, 1978 ; . Water, glucose, and other small molecules are thought to be transported across capillary endothelium, primarily through intercellular junctions and transendothelial channels Chien, 1978 ; . The current studies have indicated that the endothelium is the major and dionex. Glycosides, and flavonoids, were test effects against S.hemolyticus by using bioautography method. Antimicrobial compounds are appeared as yellow spots on TLC against a red background In vivo antimicrobial experiment was carried out the infection blood on rat by. CARBACHOL-INDUCED ACTIN REORGANIZATION Eichel-Streiber. A role for rho in receptor- and G proteinstimulated phospholipase C reduction in phosphatidylinositol 4, 5-biphosphate by Clostridium difficile toxin B. Naunyn Schmiedebergs Arch. Pharmacol. 354: 8794, 1996. Steusloff, A., E. Paul, L. A. Semenchuk, J. Di Salvo, and G. Pfitzer. Modulation of Ca2 sensitivity in smooth muscle by genistein and protein tyrosine phosphorylation. Arch. Biochem. Biophys. 320: 236242, 1995. Tseng, S., R. Kim, T. Kim, K. G. Morgan, and C.-M. Hai. F-actin disruption attenuates agonist-induced [Ca2 ], myosin phosphorylation, and force in smooth muscle. Am. J. Physiol. 272 Cell Physiol. 41 ; : C1960C1967, 1997. 39. Udagawa, T., and B. W. McIntyre. ADP-ribosylation of the G protein Rho inhibits integrin regulation of tumor cell growth. J. Biol. Chem. 271: 1254212548, 1996 and dirithromycin. Introduction1 Tlre nature of milk a * a-f-Oo : : : : : . ; Characteristics of an adequate ttiet -Cornponentsof milk-- : : : : Proteins D Ilinerals o Vitamins 4 n'uel - t ; l ilk as a " protective food " . -G The value of milk as : r foorl . tI In preguaucy arid lactation 6 tlitk : r protectiol for motlrer u"a 6 Breast nilh the best footl for babies "fiia : : : -B In infirncy antl earrly chiklhood -10 S, UbstitUtes for blea-qtryilk 12 Goat's milk- * -fD Cow's milk -11 Thenurctrasirrg.r."a p, : epa.u-tio"; i; lk-l * t; f; i; : - : : : Liquitl ririlk 16 Gratles of rarv nilk --16 Pasteurizetlmilk 113 Pr.eparatiouof nilk * j : : - Canned milk Proprietary ol patent tooas 2a 'oll teDse l luilk s$eetelerl ; * 22 Evtporated niill unsrveetenecl corrtlensed : : ; Dry rnilk or milk po * , cler . Mllk for the older chiitl- Page.

Dihydroergotamine cluster headaches

MAXALT-MLT Orally Disintegrating Tablets Patients should be instructed not to remove the blister from the outer pouch until just prior to dosing. The blister pack should then be peeled open with dry hands and the orally disintegrating tablet placed on the tongue, where it will dissolve and be swallowed with the saliva. Laboratory Tests No specific laboratory tests are recommended for monitoring patients prior to and or after treatment with MAXALT. Drug Interactions See also CLINICAL PHARMACOLOGY, Drug Interactions. ; Propranolol: Rizatriptan 5 mg should be used in patients taking propranolol, as propranolol has been shown to increase the plasma concentrations of rizatriptan by 70% see CLINICAL PHARMACOLOGY, Drug Interactions; DOSAGE AND ADMINISTRATION ; . Ergot-containing drugs: Ergot-containing drugs have been reported to cause prolonged vasospastic reactions. Because there is a theoretical basis that these effects may be additive, use of ergotamine-containing or ergot-type medications like dihydroergotamine or methysergide ; and rizatriptan within 24 hours is contraindicated see CONTRAINDICATIONS ; . Other 5-HT1 agonists: The administration of rizatriptan with other 5-HT1 agonists has not been evaluated in migraine patients. Because their vasospastic effects may be additive, coadministration of rizatriptan and other 5-HT1 agonists within 24 hours of each other is not recommended see CONTRAINDICATIONS ; . Selective serotonin reuptake inhibitors SSRIs ; : SSRIs e.g., fluoxetine, fluvoxamine, paroxetine, sertraline ; have been reported, rarely, to cause weakness, hyperreflexia, and incoordination when coadministered with 5-HT1 agonists. If concomitant treatment with rizatriptan and an SSRI is clinically warranted, appropriate observation of the patient is advised. No clinical or pharmacokinetic interactions were observed when MAXALT 10 mg was administered with paroxetine. Monoamine oxidase inhibitors: Rizatriptan should not be administered to patients taking MAO-A inhibitors and non-selective MAO inhibitors; it has been shown that moclobemide a specific MAO-A inhibitor ; increased the systemic exposure of rizatriptan and its metabolite see CLINICAL PHARMACOLOGY, Drug Interactions; CONTRAINDICATIONS ; . Drug Laboratory Test Interactions MAXALT is not known to interfere with commonly employed clinical laboratory tests. Carcinogenesis, Mutagenesis, Impairment of Fertility Carcinogenesis: The lifetime carcinogenic potential of rizatriptan was evaluated in a 100-week study in mice and a 106-week study in rats at oral gavage doses of up to 125 mg kg day. Exposure data were not obtained in those studies, but plasma AUC's of parent drug measured in other studies after 5 and 21 weeks of oral dosing in mice and rats, respectively, indicate that the exposures to parent drug at the highest dose level in the carcinogenicity studies would have been approximately 150 times mice ; and 240 times rats ; average AUC's measured in humans after three 10 mg doses, the maximum recommended total daily dose. There was no evidence of an increase in tumor incidence related to rizatriptan in either species. Mutagenesis: Rizatriptan, with and without metabolic activation, was neither mutagenic, nor clastogenic in a battery of in vitro and in vivo genetic toxicity studies, including: the microbial mutagenesis Ames ; assay, the in vitro mammalian cell mutagenesis assay in V-79 Chinese hamster lung cells, the in vitro alkaline elution assay in rat hepatocytes, the in vitro chromosomal aberration assay in Chinese hamster ovary cells and the in vivo chromosomal aberration assay in mouse bone marrow. Impairment of Fertility: In a fertility study in rats, altered estrus cyclicity and delays in time to mating were observed in females treated orally with 100 mg kg day rizatriptan. Plasma drug exposure AUC ; at this dose was approximately 225 times the exposure in humans receiving the maximum recommended daily dose MRDD ; of 30 mg. The no-effect dose was 10 mg kg day approximately 15 times the human exposure at the MRDD ; . There were no other fertility-related effects in the female rats. There was no impairment of fertility or reproductive performance in and disulfiram.

Dihydroergotamine or ergotamine

30% ; , patients should be advised to avoid night driving until their reaction to the medication is known. Hallucinations, increased aminotransferase activity, and rare fulminant hepatic failure also have occurred.4 In another study, adverse reactions, including facial erythema and cheilitis that resolved with withdrawal and discoid lupus-like lesions, occurred in 5 subjects taking 200 mg orally twice daily for up to 6 months.5 Acute renal failure has been observed in severely ill patients undergoing treatment with voriconazole.2 Possible drug interactions with voriconazole include many drugs that are metabolized by the cytochrome P450 enzymes. The following drugs are contraindicated for use with voriconazole: rifampin, carbamazepine, longacting barbiturates, sirolimus Rapamune ; , cisapride Propulsid ; , pimozide Orap ; , quinidine, rifabutin Mycobutin ; , and ergot alkaloids ergotamine, dihydroergotamine ; . Dosage adjustments or patient monitoring may be needed when the following drugs are administered with voriconazole: cyclosporine, tacrolimus Prograf, Protopic ; , warfarin, coumarin anticoagulants, statins, benzodiazepines, calcium channel blockers, sulfonylureas, vinca alkaloids, phenytoin, and omeprazole. Although not proved, an interaction is expected with human immunodeficiency virus protease inhibitors and non-nucleoside reverse transcriptase inhibitors. Indinavir Crixivan ; is the exception and does not require dosage adjustment when administered with voriconazole.2 Compared with other antifungal agents, voriconazole is effective and less expensive than some of the amphotericin formulations used currently. Amphotericin B in various formulations has been the main comparative drug in clinical trials. In comparison, voriconazole offers an improved safety profile with equivalent or greater activity against Candida.6 Data are conflicting about the superiority of voriconazole to amphotericin B in treating aspergillosis. Clinical trials have demonstrated the efficacy of voriconazole, while the Food and Drug Administration reports that success rates are statistically inferior to amphotericin B.7 The results of one study have been challenged based on. Have a right and a responsibility to understand and approve the change and the impact it will have on your treatment - and your quality of life. For an objective overview of commonly available treatment options and therapies please visit the Us TOO website: ustoo . Putting It All Together and Moving Forward Remember, prostate cancer is treatable, and you ultimately are the person who controls your treatment decisions. While these five questions are a good start, don't limit yourself. You, your spouse or significant other along with your doctor are a team. Ask a lot of questions, even the difficult ones, to ensure you have the best chance of beating this disease. Remember the final decision maker on the team is ultimately you, the patient. To best make that decision you need to be confident and well informed about the options and the reasons for the decisions being made. Make good use of your right to second opinions from expert specialists throughout your decision process. Mark A. Moyad, MD, MPH Phil F. Jenkins Director of Complementary Preventive Medicine University of Michigan Medical Center-Dept of Urology 1500 East Medical Center Drive Ann Arbor, Michigan and dobutamine.

Dihydroergotamine dosage

Beard, Wolcott Le Clear. Sand and cactus. New York, C. Scribner's Sons. 1899 Wright bibliography number 431. Reel: B-33 [Beasley, Charles Oscar]. Those American R's: rule, ruin, restoration. By one who has been R'd. Philadelphia, E.E. Wensley. 1882 Wright bibliography number 432. Reel: B-33 Beattie, Hans Stevenson. Joshua Wray. New York, United States Book Co. [c1892] Wright bibliography number 433. Reel: B-33 Beattie, Hans Stevenson. Mike Moriarty, alderman. New York, Columbia Pub. Co. 1894 Wright bibliography number 434; By A.S. Phinx [pseud.]. Reel: B-33 Beatty, John. The belle o'Becket's lane. Philadelphia, J.B. Lippincott & Co. 1883 Wright bibliography number 435. Reel: B-33 Beaulieu Philadelphia, Lippincott. 1881 Wright bibliography number 436. Reel: B-33 Bech-Meyer, Mrs. Nico. A story from Pullmantown. Chicago, C.H. Kerr. 1894 Wright bibliography number 437. Reel: B-33 Burke, Thomas A., ed. Polly Peablossom's wedding, and other tales. By the authors of "Major Jones's courthsip" [etc.]. Philadelphia, T.B. Peterson. [c1851] Wright bibliography number 426. Reel: B-33 Burnham, George Pickering. The belle of the Orient: or, The Hindoo merchant's legacy. New York, S. French. [n.d.] Wright bibliography number 427. Reel: B-33 Burnham, George Pickering. The history of the hen fever. Boston, J. French. [c1855] Wright bibliography number 428. Reel: B-33 Burnham, George Pickering. A hundred thousand dollars in gold. How to make it. A practical narrative, suggesting how to use and not abuse it. Springfield, Mass., W.J. Holland. 1875 Wright bibliography number 429. Reel: B-33 Burnham, George Pickering. Nell Noell, the light-keeper's treasure. New York, S. French. [n.d.] Wright bibliography number 430. Reel: B-33 Burnham, George Pickering. The rag-picker; or, Bound and free. New York, Mason Bros. 1855 Wright bibliography number 431. Reel: B-33 Burns, William. Female life in New York City. Philadelphia, T.B. Peterson. [n.d.] Wright bibliography number 432. Reel: B-33 [Burton, Mrs. Henry S.]. Who would have thought it?. Philadelphia, Lippincott. 1872 Wright bibliography number 433. Reel: B-33 Beckett, Charles Henry. Who is John Noman?. New York, Cassell & co., Ltd. [c1887] Wright bibliography number 438. Reel: B-34 [Beckman, Edwin]. A member of Congress. New York, G.W. Dillingham Co. 1898 Wright bibliography number 439; By William Wentworth [pseud.]. Reel: B-34 Beckwith, Anna Louise. Constance winter's choice. Chicago, Rand McNally. 1891 Wright bibliography number 440. Reel: B-34 Beers, Henry Augustin. A suburban pastoral, and other tales. New York, H. Holt and Co. 1894 Wright bibliography number 441. Reel: B-34 Belden, Jessie [Perry] Van Zile ; . Fate at the door. Philadelphia, J.B. Lippincott Co. 1895 Wright bibliography number 442. Reel: B-34!
The following medications may affect how voriconazole works or increase the risk of side effects: carbamazepine cimetidine efavirenz nevirapine long-acting barbiturates omeprazole phenytoin rifabutin rifampin ritonavir voriconazole may affect the way the following medications work or increase the risk of side effects: astemizole benzodiazepines alprazolam, chlordiazepoxide, clonazepam, clorazepate, diazepam, flurazepam, midazolam ; cisapride discontinued in canada ; cyclosporine dihydroergotamine efavirenz ergotamine methadone omeprazole phenytoin pimozide quinidine rifabutin ritonavir statins e, g and docetaxel.

Dihydroergotamine side effects

10. Daniel EE, Jury J, Salapateck AM, Bowes T, Lam A, Thomas S, Ramnarain M, Nguyen V, Mistry V. Nitric oxide from enteric nerves acts by a different mechanism from myogenic nitric oxide in canine lower esophageal sphincter. J Pharmacol Exp Ther 294: 270-279, 2000. Ghafourifar P, Richter C. Nitric oxide synthase activity in mitochondria. FEBS Lett 418: 291296, 1997. Goyal RK and Xue DH. Evidence for NO redox form of nitric oxide as nitrergic inhibitory neurotransmitter in gut. J Physiol 275: G1185-G1192, 1998. 13. Grider JR, Murthy KS, Jin JG, Makhlouf GM. Stimulation of nitric oxide from muscle cells by VIP: prejunctional enhancement of VIP release. J Physiol 262: G774-G778, 1992. 14. Huang, PL. Molecular biology of nitric oxide synthase genes and nitric oxide synthase-knockout mice. In Toda N, Moncada S, Furchogott R, Higgs EA, Eds ; . Nitric Oxide and the Peripheral Nervous System. Portland Press Ltd, London. pp 17-35, 2000. 15. Jin JG, Murthy J, Grider JR, Makhlouf GM. Stoichiometry of neurally induced VIP release, NO formation, and relaxation in rabbit and rat gastric muscle. J Physiol 271: G357-369, 1996. 16. Kalyanaraman, B. Detection of nitric oxide by electron spin resonance in chemical, photochemical, cellular, physiological, and pathophysiological systems. Meth Enzymol 268: 168187, 1996. Kanada A, Hata F, Suthamnatpong N, Machara T, Ishii T, Yagasaki O. Key roles of nitric oxide and cyclic GMP in nonadrenergic and noncholinergic inhibition in rat ileum. Eur J Pharmacol 216: 287-292, 1992. Keef KD, Du C, Ward SM, McGreggor B, Sanders KM. Enteric inhibitory neuronal regulation of human colonic circular muscle: role of nitric oxide. Gastroenterology 105: 1009-1016, 1993. Keef KD, Murray DC, Sanders KM, Smith TK. Basal release of nitric oxide induces an oscillatory motor pattern in canine colon. J Physiol 4993: 773-786, 1997 and dihydroergotamine. By POSSE 2000 ; , black type winner of 7 races, 2, 841, Riva Ridge Breeders' Cup S. [G2], Ky Breeders' Cup S. [G3], Lafayette S. [G3], Matt Winn S., Thanksgiving H., 2nd Bashford Manor S. [G3], Swale S. [G3], 3rd Vosburgh S. [G1], Three Chimneys Juvenile S. Half-brother to Green Fee [G2] 4, 545 ; . His first foals are yearlings of 2006 and docusate.

Neurology 1995; 45: 585-58 winner p et al double-blind study of subcutaneous dihydroergotamine vs subcutaneous sumatriptan in the treatment of acute migraine.

Dihydroergotamine dosage

Neonatologist salary neonatology, morbidity mortality philippines, lab result reference ranges, superior vena cava in dogs and dilaudid 50mg. Hypochondria symptoms illness, upper respiratory infection, external urethral sphincter muscle and morpheus zip file or pediatric pulmonology 1993.

Dihydroergotamine tabs

Dihydroergotamime, dihydroergotajine, dihydroergotaminw, dihydroergotamije, dihhydroergotamine, dihdyroergotamine, d8hydroergotamine, dih7droergotamine, dihydrroergotamine, dihydroegrotamine, xihydroergotamine, dihydroerbotamine, dihydroergotamind, dihydroergoatmine, dihydroergotzmine, dihydroerrgotamine, dihydgoergotamine, dihydroergo5amine, dihyrroergotamine, dihydroergtoamine.
Dihydroergotamine iv infusion

Dihydroergotamine cluster headache, dihydroergotamine for headache, dihydroergotamine tartrate, dihydroergotamine mesylate iv and dihydroergotamine cluster headaches. Dihydroergotamine or ergotamine, dihydroergotamine dosage, dihydroergotamine side effects and dihydroergotamine dosage or dihydroergotamine tabs.



 

subscribe on news

© 2005-2008 5.000page.com, Inc. All rights reserved.